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KMID : 1007520090180020533
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Food Science and Biotechnology
2009 Volume.18 No. 2 p.533 ~ p.536
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Establishment of Withdrawal Time of Erythromycin for the Cultured Black Rockfish (Sebastes schlegeli) after Oral Administration
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Park Mi-Jung
Choi Kyu-Duck
Lee Tae-Seek
Choi Hye-Sung
Shim Kil-Bo
Myeong Jeong-In
Park Mi-Seon
Shin Il-Shik
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Abstract
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Withdrawal time of erythromycin in the cultured black rockfish (Sebastes schlegeli) was investigated to provideregulatory authority and fishery industry with full information needed to secure food safety of the fish treated witherythromycin. Medication was carried out using the experimental diet containing erythromycin of which concentration was200 mg/kg diet and its daily dose was about 40 mg/kg body weight. The withdrawal time needed to reduce antibiotic contentsaround 10.0 mg/kg accumulated during 9 days medication below 0.2 mg/kg was identified about 10 days. The antibiotic with13.7 mg/kg of fish on the 9th days of medication was completely depleted after 30 days from stop of medication.
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KEYWORD
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erythromycin, liquid chromatography tandem mass spectrometry, black rockfish, withdrawal time
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